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Even though the opiate receptor relies on G protein coupling for signal transduction, this receptor was discovered to make use of arrestin activation for internalization of the receptor. Normally, the receptor promoted no other signaling cascades (fifty nine) Modifications of conolidine have resulted in variable enhancement in binding efficacy. Thi
While the opiate receptor relies on G protein coupling for sign transduction, this receptor was found to benefit from arrestin activation for internalization of the receptor. Or else, the receptor promoted no other signaling cascades (59) Modifications of conolidine have resulted in variable advancement in binding efficacy. This binding ultimately